Background: BMSC-secreted exosomes (BMSC-Exos) have shown potential for promoting behavioral recovery following spinal cord injury (SCI).However, its role in blocking astrocyte activation remains unclear.Thus, this study aimed to determine whether BMSC-Exos impair the function of astrocytes following SCI in mice and to seek the mechanism.Methods: B
Background and purpose: Oral squamous cell carcinoma (OSCC) is the most common subtype of head and neck squamous cell carcinoma (HNSCC), and its pathogenesis is unclear.Nucleolar protein 8 (NOL8), as one of the RNA-binding protein (RBP), plays a key role in the occurrence and development of many kinds of tumors, however its role in OSCC is not clea
Epithelial tissue responds rapidly to environmental fbd191blrc triggers and is constantly renewed.This tissue is also highly accessible for therapeutic targeting.This review highlights the role of connexin mediated communication in avascular epithelial tissue.These proteins form communication conduits with the extracellular space (hemichannels) and
AbstrakPenderita keganasan mendapat kemoterapi banyak menunjukkan gejala psikologisseperti ansietas dan depresi yang sangat berpengaruh terhadap kepatuhan penderita dalammenjalani kemoterapi.Penelitian ini bertujuan untuk melihat hubungan mekanisme kopingdengan kepatuhan melakukan kemoterapi pada penderita keganasan yang mengalamiansietas dan depre
AIM: Accumulating evidence suggests that extracellular galectin-1 and galectin-3 promote angiogenesis.Increased expression of galectin-1 and/or galectin-3 has been reported to be associated with tumour progression.Thus, it is critical to identify their influence on angiogenesis.METHODS: We examined the individual and combined effects of galectin-1